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Treatment Details

Systemic Lupus

Overview

Systemic Lupus Erythematosus (SLE) is the most prevalent form of lupus which is classified as an autoimmune disease that has no known cure. Some of the symptoms are tiredness, joint aches, and rashes with regions involving nostrils and cheeks. There is no cure for it, but it can be treated, meaning that, with the appropriate care, a person can live a normal life. Autoimmune disease happens when the body’s immune system turns against it, resulting from perceiving the body as an outsider. Autoimmune diseases can be categorized as common and rare; however, there are numerous autoimmune diseases, such as systemic lupus erythematosus.

Many immunological conditions that are characterized by similar clinical manifestations and laboratory findings have been referred to as lupus collectively, but SLE is the most prevalent form of lupus. SLE is a long-term condition with some periods having serious symptoms and other times having relatively moderate symptoms. SLE can scarcely limit a patient’s functionality and overall lifestyle as long as they undergo treatment.

Symptoms of Systemic Lupus

Symptoms for SLE can vary and can change over time. Some of the common symptoms include:

Severe fatigue
Joint pain
Joint swelling
Headaches
Rash on the cheeks and nose
Hair loss
Anemia
Blood-clotting problems
Fingers turning white or blue and tingling when cold

Additional symptoms may vary depending on whatever bodily component the disease is targeting, such as the skin, heart, or digestive system.

Diagnosis of Systemic Lupus

SLE is difficult to diagnose due to its flare/remission cycle and overlapping symptoms. A detailed medical history and lab testing are necessary.

Diagnostic Tests:

History: Joint pain, rashes, fatigue, sun sensitivity
ANA Test: Positive in 70% of cases
Autoantibodies: Anti-dsDNA, anti-Smith, Ro/SSA, La/SSB
CBC: Check for anemia, leukopenia, thrombocytopenia
ESR and CRP: Inflammation markers
Urinalysis: Protein and blood in urine (kidney disease)
Imaging: X-rays, Ultrasound, MRI (organ/joint evaluation)
Kidney Biopsy: For lupus nephritis cases

Causes of Systemic Lupus

Causes of Systemic Lupus Erythematosus include the following:

Environmental Factors
Genetic Factors
Hormonal Factors

SLE is a chronic long-standing disease whose manifestations flare up at one time as opposed to other times. Modern medications allow most of the patients with SLE to live a normal life.

Treatment Options / Stages of Systemic Lupus

Treatments Options:

Managing symptoms
Reducing and reversing flares
Minimizing organ damage
Extending life expectancy
Medications:

NSAIDs: For minor inflammation and pain
Antimalarials: Hydroxychloroquine for skin/joint issues
Corticosteroids: Doses depend on severity
Immunosuppressants: Methotrexate, azathioprine for severe cases
Biologics: Belimumab for patients unresponsive to other treatments

Alternative and Complementary Therapies:

Acupuncture
Chiropractic treatment
Homeopathy
Special diets
Nutritional supplements
Fish oils
Ointments and creams

Note: Consult a physician before starting any alternative treatments.

Frequently Asked Questions

Q: How long does a person with systemic lupus expect to live? A: 85–90% of lupus patients may have a normal lifetime with early diagnosis, cautious management, and ongoing monitoring. Q: Which SLE therapy is the first line of treatment?
A: For skin disease: Topical calcineurin inhibitors, glucocorticoids, and antimalarials (hydroxychloroquine). Systemic glucocorticoids may also be used.

Q: Can sudden death occur from SLE?
A: Major causes of death include cancer and cardiovascular issues. Infections are less frequent now due to medical advances.

Q: What are lupus’s terminal stages?
A: Severe damage to kidneys (lupus nephritis), heart inflammation, and other organs can reduce life expectancy.

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Once you leave enquiry with Medi Venture Care, we assign you a dedicated case manager who will organise everything for you thereafter – including hotel booking, airport transfers, online consultation with doctors etc. Treating doctor asks for detailed history of the patients, chronology of investigations done, treatments undertaken, current symptoms to arrive at the right line of treatment and share the expected cost of treatment.

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Treating doctor asks for detailed history of the patients, chronology of investigations done, treatments undertaken, current symptoms to arrive at the right line of treatment and share the expected cost of treatment.